Association Between Intra-abdominal Pressure and Necrotizing Enterocolitis

Association Between Intra-abdominal Pressure and Necrotizing Enterocolitis
Principal Investigator	Karen A. Diefenbach, MD
Investigator	R. Lawrence Moss, MD
Clinical Epidemiologist	Bonnie Lang Silverman, PhD

Project Goal

Current

To demonstrate the feasibility of measuring intra-abdominal pressures via indwelling bladder catheter in neonates requiring emergent surgery for NEC
To determine if intra-abdominal pressures are elevated in neonates requiring emergent surgery for NEC.

Future plans

To determine if there is a correlation between intra-abdominal pressures and severity of disease in premature infants with necrotizing enterocolitis.

Study Design

Prospective feasibility study (1) to be followed by longitudinal study (2) of infants with NEC.

Data Collection

Indirect measurement of intra-abdominal pressures via indwelling bladder catheter and transducer. Documentation via data collection forms designed specifically for the study

Data Management

Stata V 9.0

Funding

pending

Timeline

Start date: Dec, 2005

End date: May, 2006

Status: Jan 2006

Data collection for feasibility study is in progress.
Protocol for longitudinal study under development.